Historical Context
The life of Vitalius is set in early seventh-century Alexandria. According to the synaxarion, he arrived in the city during the patriarchate of John the Merciful (John the Almsgiver), who served as Patriarch of Alexandria in the early 600s, fixing the events of Vitalius's later years within that period.
His repose is dated to around the year 625. The Eastern Orthodox Church commemorates him on April 22 and January 11; in the Western calendar his feast is kept on January 11.