Defense of Nicene Orthodoxy
Ambrose was a forceful opponent of Arianism throughout his episcopate. He worked to install bishops of Nicene conviction, presided over the Council of Aquileia in 381 that deposed the Arian bishops Palladius and Secundianus, and persuaded the emperor Gratian to support the Nicene confession, presenting him with the treatise De Fide.
His best-known confrontation came in 385-386, when the Arian imperial court demanded the surrender of Milan's churches for Arian worship. Ambrose refused, maintaining the principle that what belongs to God lies outside the emperor's authority, and held out with his congregation until the order was rescinded. He likewise required public penance of the emperor Theodosius I after the massacre at Thessalonica in 390, treating emperor and commoner alike in matters of repentance.