Patriarch under Ottoman Rule
Niphon's patriarchate fell within the precarious period after the fall of Constantinople, when the Ecumenical throne depended on Ottoman sanction and the patronage of Orthodox princes beyond the empire. He served three separate terms, generally dated 1486–1488 and 1497–1498, with a third election in 1502.
His first elevation came with the support of Wallachia, and his second with the backing of the Wallachian ruler Radu the Great. Each tenure ended in deposition: he was banished in 1488, and after his second term he was again removed and exiled, the sources naming Adrianople as the place of his exile. When the Holy Synod elected him a third time in 1502, he declined to resume the office and did not return to the capital.